A 75 yr old male with altered sensorium

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CASE:

A 75 years old diabetic male came to casualty with c/o altered sensorium.

CHIEF COMPLAINTS:

Unresponsiveness and difficulty in breathing since previous night.

HOPI:

Patient was apparently asymptomatic before the previous evening, he had his dinner and slept. Around midnight he made some sounds ( like snoring) and had involuntary movements for 2minutes and was unconscious and unresponsive.
Altered sensorium of sudden onset.
No h/o tongue bite, involuntary micturition.
No h/o previous seizures.
No h/o of vomiting and  headache.

PAST HISTORY:

No similar complaints in past.
He is a k/c/o of Diabetes since 10 years and is on medication for the same. (? unknown)
Not a k/c/o HTN, CVA, CAD, TB, EPILEPSY, ASTHMA.


PERSONAL HISTORY:

  1. Diet- Mixed
  2. Appetite- Normal
  3. Bowel and bladder movements- Regular
  4. Sleep- Adequate
  5. Addictions- H/o alcohol consumption occasionally which hestopped 3years ago; cigarette smoking for 15years stopped 3 years ago.
  6. Surgical history-No h/o previous surgeries.

FAMILY HISTORY:

Not significant.

GENERAL EXAMINATION:

The patient was examined in a well-lit room after informed consent was taken.

The patient is unconscious.

He is well nourished and moderately built.

No Pallor, Icterus, Clubbing, Cyanosis, Koilonychia, Lymphadenopathy, Edema.

No signs of malnutrition/ dehydration.

VITALS:
  1. Temp-102°F
  2. PR-111bpm
  3. RR-20cpm
  4. BP-140/80mmHg 
  5. SpO2-98% on 14L O2
  6. GRBS- 329mg/dL
SYSTEMIC EXAMINATION:
  1. CVS- S1, S2 Heard
  2. RS- BAE+, BARREL shaped chest present, B/L crepts heard in all lung fields.
  3. P/A-  scaphoid, non tender, no organomegaly.
  4. CNS-
  • Level of consciousness- COMA
  • GCS- E1M1V1
  • Pupil are mid dilated, unresponsive to light.
  • Gag reflex PRESENT
  • Neck stiffness PRESENT.
  • REFLEXES-   LEFT            RIGHT
  1. Biceps               2+                  2+ 
  2. Triceps.            2+                   2+
  3. Supinator        2+                   2+
  4. Knee.                 1+.                 1+
  5. Ankle                2+.                  2+
  6. Plantar.         Withdrawal     Mute



INVESTIGATIONS:

HEMOGRAM


PROTHROMBIN TIME


KETONE BODIES


COMPLETE URINE EXAMINATION


HEPATITIS C


HEPATITIS B


ARTERIAL BLOOD GASES


HIV


RANDOM BLOOD SUGAR



RENAL FUNCTION TEST



GLYCATED HEMOGLOBIN


SERUM ELECTROLYTES


APTT


LIVER FUNCTION TEST


ECG



CT BRAIN




PROVISIONAL DIAGNOSIS:

Hypodensity of bilateral Cerebellar and Brainstem with ? VIRAL MENINGITIS, ? AKI 2° to SEPSIS, ? Aspiration Pneumonia, ? consolidation.

TREATMENT:


7/11/2021
  1. IVF- NS and RL @ 75ml/hr
  2. Inj. PIPTAZ 4.5g IV STAT then 2.25 IV/QID
  3. Inj. NEOMOL 1g IV/SOS (if temperature>101°F)
  4. Inj. PAN 40mg IV/OD
  5. Inj. ZOFER 4mg IV/TID
  6. Inj. OPTINEURON 1amp in 100ml ND IV/OD
  7. RT feeds-2nd hourly (3 scoops protein powder+ 150ml milk)
  8. ET/Oral suctioning- 3 hourly
  9. Inj. MIDAZ - 1mg/kg/hr (~60kg);                            no dilution- 1mg-1ml                                  1.2ml-6ml/hr(max dose)
  10. Inj. LEVIPIL 500mg IV/BD
  11. Air/ water bes
  12. Change of position every 2nd hourly
  13. DVT stockings
8/11/2021
  1. IVF- NS and RL @ 75ml/hr
  2. Head end elevation upto 30°
  3. Inj. NEOMOL 1g IV/SOS (if temperature>101°F)
  4. Inj. OPTINEURON 1amp in 100ml ND IV/OD
  5. Inj. PAN 40mg IV/OD
  6. Inj. ZOFER 4mg IV/TID
  7. Inj. LEVIPIL 500mg IV/BD
  8. Inj. DEXA 4mg/IV/BD
  9. Inj. ACYCLOVIR 500mg IV/TID
  10. RT feeds-2nd hourly (free water-100ml + protein powder-100ml)
  11. ET/Oral suctioning- 3 hourly
  12. Strict I/O charting- 2nd hourly
  13. BP, PR , SpO2 charting- hourly
  14. Inj. CEFTRIAXONE 2g/IV/BD
  15. Inj. MANNITOL 100mL/IV/BD
9/11/2021
  1. IVF- NS and RL @ 75ml/hr
  2. Head end elevation upto 30°
  3. Inj. NEOMOL 1g IV/SOS (if temperature>101°F)
  4. Inj. OPTINEURON 1amp in 100ml ND IV/OD
  5. Inj. PAN 40mg IV/OD
  6. Inj. DEXA 4mg/IV/BD
  7. Inj. ACYCLOVIR 500mg IV/TID
  8. RT feeds-2nd hourly (free water-100ml + protein powder-100ml)
  9. ET/Oral suctioning- 3 hourly
  10. Inj. CEFTRIAXONE 2g/IV/BD
  11. Inj. MANNITOL 100mL/IV/BD
  12. Strict I/O charting- 2nd hourly
  13. BP, PR , SpO2 charting- 4thhourly









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